What’s the longest-lasting vehicle in the U.S.? If you said a Toyota or Honda, guess again. In the latest analysis, it’s the Ram 3500 pickup truck that has the best chance of hitting 250,000 miles. But the Ram 3500 isn’t actually from the U.S. Every heavy-duty Ram truck is assembled in Saltillo, Mexico.

Ram 3500 tops Toyota in latest longevity rankings

Every year, the analysts at iSeeCars.com analyze the sales data of over 100 million vehicles to rank the makes and models most likely to hit 250,000 miles. Normally, Toyota and Lexus models sweep the list. But we have a surprise winner for 2025. The Ram 3500 has a 39.7% chance of hitting 250,000 miles. That’s over three times as likely as the average pickup truck. It’s even better odds than the Toyota Sequoia (39.1%) and the Toyota 4Runner (32.9%).

Most heavy-duty pickup trucks are statistically likely to hit 250,000 miles. The Ford F-450 Super Duty has a 28.5% chance of seeing ultra-high mileage. The GMC Sierra 2500 HD has a 22% chance.

Chrysler Corporation opened its first plant in Mexico in 1968. It finished its Saltillo assembly plant in 1995, and that factory began building heavy-duty trucks in 2005. Today, every single heavy-duty Ram (2500 and larger) hails from Saltillo. The trucks’ gasoline-powered engine options are also built in Mexico, though the Cummins I6 turbodiesel option is still made in Columbus, Indiana. Ram still builds many of its half-ton “1500” trucks in Sterling Heights, Michigan. But the truck manufacturer may be about to abandon Detroit for Mexico even harder.

Curious where your car or truck was built? If its VIN starts in 1, 4, or 5, it was assembled in the U.S. If the number is a 2, it stands for Canada, and 3 means Mexico.